143 Magnesium in medicine with Declan

Hi Everyone,

This week I sat down with Declan to discuss a fascinating therapy which is used in many areas of medicine.

This podcast has a bit of everything, a quiz, a part one viva, dubious animal experimentation, discussions about laxatives, and even some references to cosmology and the Big Bang.

Thanks Declan for another entertaining episode.

2 thoughts on “143 Magnesium in medicine with Declan

  1. Hi team! Great podcast as always!
    Just wanted to note a few things so yes we do monitor serum magnesium six hourly if a patient is on an infusion, looking to keep the magnesium plasma levels between 1.7 and 3.5 which is the sort of well documented therapeutic range of magnesium, especially in the setting of eclampsia. Additionally in patients with renal failure whilst there’s no good guidelines generally in Queensland I use a creatinine of above sort of 77 to 80 and I will half the maintenance dose to half a gram.
    Look, these are local protocols and maybe different in W.A. but this is what we do in Queensland

    1. Thanks Tim,
      We should have discussed monitoring of plasma levels and what to do when there is renal impairment – which happens with pre-eclampsia. I had a quick look at our guidelines here at KEMH – we don’t require routine monitoring of plasma levels – however it is mandatory to check levels if there is oliguria / renal impairment or loss of deep tendon reflexes (which are part of the routine obs every hour). Our guideline https://www.kemh.health.wa.gov.au/~/media/HSPs/NMHS/Hospitals/WNHS/Documents/Clinical-guidelines/Obs-Gyn-Guidelines/Hypertension-and-Pregnancy.pdf?thn=0
      All women on magnesium have to be monitored closely 1:1 either in labour ward or our HDU. Thanks Tim!

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